1963: joined the Philharmonia Orchestra as a violinist.
1964: joined the Academy of St Martin in the Fields.
1974: became soloist and director of the Academy of St Martin in the Fields.
1981: artistic director of the Norwegian Chamber Orchestra
1985 to 1989: guest director of the City of Birmingham Symphony Orchestra.
1987: artistic director of the Los Angeles Chamber Orchestra.
Restricted by rheumatoid arthritis in her wrists, she turned increasingly to conducting giving her final concert as a conductor came in May 2002, with the London Philharmonic Orchestra, on the day that she received a diagnosis of cancer.