Santiago Niño was born in Colombia and is now living in Guatemala. He began producing at the age of 16, developing his unique musical style through the influences of everything from hard techno to progressive house. His first 'bootleg' remixes were a huge success, landing in the hands of producers such as Marco Carola, Chris Liebing, Greg Benz, and Ozgur Can.

Formerly known as DJ Cuttof, Santiago decided to launch his professional career as a musician using his legal name. He signed his first remix to Seductive Recordings with production partner Francis Davila. Since that time, Santiago's original productions and remixes have been played by such talented DJ's as Mauro Picotto, Ricky Effe, Preach, Marcello Castelli, Martin Accorsi, Markus Schulz, DJ Misjah, Marko Nastic, Redhead, Perry O'Neal, Max Graham, Matthew Dekay, Sander Kleinenberg, Cari Lekebusch, and Armin van Buuren.

Santiago has begun to explore the softer side of dance music with some of his more recent productions, drawing inspiration from progressive house artists such as Ozgur Can.