Miss Derringer is heavily influenced by American music of the late 50s and early 60s - particularly the vintage sounds of outlaw country, early 60s girl group pop.
The band's lyrics deal with "honkytonk" subjects like prison, poverty, sobriety, God, death, marriage, murder, and alcohol.
Miss Derringer has opened up for several notable acts including Bad Religion, Blondie, John Doe, IAMX and Tiger Army.
Miss Derringer has released two albums with Sympathy for the Record Industry. The first King James, Crown Royal, and a Colt 45 was released in 2004.
Their second album "Lullabies" includes guest musicians such as drummer Clem Burke from Blondie and was co-produced by Derek O'Brien of Social Distortion and The Adolescents.
In 2007, Miss Derringer released the 2 song ep "Black Tears" electronically, on Stay Gold Records. Black Tears was produced by John Kastner of the Doughboys and All Systems Go! The song "Black Tears" and its remix version have been featured on the television show How I Met Your Mother
In 2008 the band signed a "strategic partnership" marketing deal with noted Advertising Agency Deutsch Inc. In late 2008 Miss Derringer was selected by Morgans Hotel Group as one several bands to participate in their "Recess is on" campaign, and was filmed performing a live version of their song "better Run Away From Me" at the Mondrian Hotel in Los Angeles.
In February 2009 Miss Derringer signed a record deal with Los Angeles label Triple X Records, who released the band's third album "Winter Hill" in July 2009.