C.S.I. were founded in 1992 by Giovanni Lindo Ferretti and Massimo Zamboni, along with Gianni Maroccolo, an original member of the Italian band Litfiba.
The choice of the band's name followed the political changes occurring around the time of the fall of the Berlin wall. Whereas the earlier band's name referenced the Cyrillic lettering for SSSR (i.e. USSR), "CSI" follows the conventions of the Italian acronym for the newly-established Commonwealth of Independent States.
After Zamboni departed in 2000, the remaining members of C.S.I. went on performing under the name Per Grazia Ricevuta.