The original lineup reunited for two sold-out NYC shows in January 2003. Several concerts followed. In 2005 the band released another studio album.
In February 2012 Sal Abruscato confirmed the end of the band, however they reunited again for a show in Belgium on 8 August, 2014.
In January 2016 Life Of Agony announced the release of a new album. Sal Abruscato left the band in December 2017, he was replaced by Veronica Bellino.