Formed a vocal duo with Sam Moore in the early 1960's. Enjoyed major success when the duo was coupled with the songwriting team of Isaac Hayes and David Porter in 1965. The best known hits from this period are probably Hold On, I'm Coming (1966) and Soul Man (1967).
Sam & Dave disbanded in 1971, but reunited shortly several times during the 1970's and early 1980's. Sam & Dave were inducted into the Rock & Roll Hall of Fame in 1992.