Wine was a child prodigy who studied piano at the Juilliard School of Music before going to work at Screen Gems Publishing. There she initially collaborated with songwriters including Gerry Goffin, Howard Greenfield and Steve Venet. The first Wine composition that was recorded was The Cookies' "Only to Other People," but she needed the following three year association with Carole Bayer Sager to blossom. The earliest fruits of their partnership, "A Groovy Kind of Love," topped the U.S. Billboard Hot 100 chart in 1965. By this time Wine was also recording as a solo artist, releasing singles for Colpix Records to minimal acclaim.
By 1969, Wine joined with Ron Dante, Ellie Greenwich and Andy Kim to record as The Archies. The following year, according to some reports, Wine reunited with fellow Brill Building alum Tony Orlando to lend vocals on her song "Candida," which was nevertheless accredited to Dawn. (Some accounts also place Wine at the sessions for Orlando's follow-up, "Knock Three Times.")
After recording a handful of bubblegum flavoured tracks, in the early 1970s, Wine married the record producer, Chips Moman, and relocated to Memphis, Tennessee. There she released material for Atco Records and Monument Records in addition to a continuing career as a writer and session vocalist.
In 2007, Wine toured and appeared in concert with Tony Orlando, as vocalist and keyboardist.