He was signed to Quin Ivy's production company in 1967 and recorded a southern soul classic,"Self Preservation" that Percy Sledge covered. A second highly sought after single, "Rainbow Road", issued in 1968 was released as a one off by Tower Records. It was written about and for Arthur Alexander (You Better Move On #24 Pop, 1962) who ended up recording it four years later but Brandon's recording remains the definitive version.
Quin Ivy began to get out of the music business and Brandon began recording for Sam Dees and Frederick Knight. He then signed with Moses Dillard and Jesse Boyce, who had a production deal with Prelude Records. Brandon recorded an uptempo disco version of "Can't We Just Sit Down And Talk It Over" a song written by Tony Macaulay, that Donna Summer covered a tender ballad for her "I Remember Yesterday" LP and the B side of "I Feel Love". "We Fell In Love While Dancing" was issued on a special promotional 12" Prelude single backed with fellow Huntsville-ite Lorraine Johnson's "The More I Get The More I Want".
His last vinyl pressing was "Special Occasion / Get It While It's Hot" coming out in 1978, and since then no new music has come from Bill Brandon. He left the music business behind in 1987 and took up truck driving and like Rick Nelson's "Garden Party" with absolutely no regrets. Reports about him confirm that he is still singing for the congregation of a church in Harvest, Alabama to this day.